Below is the list of commonly recommended HPUX kernel parameters. But this may vary based on your application need.

# Parameter Value
bufpages 0 # on HP-UX 10.X
create_fastlinks 1
dbc_max_pct 25
fs_async 1
maxdsiz 2063806464
maxfiles 200
maxfiles_lim 2048
maxssiz (80*1024*1024)
maxswapchunks 4096
maxtsiz (1024*1024*1024)
maxuprc 200
maxusers 124
netmemmax 0 # on desktop systems
-1 # on data servers
nfile 2800
ninode 15000 # 4000 on HP-UX 10.20 multi-processor systems
nproc 1024
npty 512

More details at : http://docs.hp.com/en/1219/tuningwp.html#kernparmrec

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